The SyncVision Angio+ vessel enhancement tool provides clarity in visualizing vessels, which may include tortuous or overlapping vessels and highly stenosed lesions, potentially reducing the number of required views during diagnosis or therapy.
Quantitative coronary analysis
The SyncVision Angio+ quantitative coronary analysis automatically calculates lumen dimensions and stenosis in real time.
SyncVision IVUS Co-registration localization
The SyncVision IVUS Co-registration application co-registers the location of the IVUS image on the angiogram and provides easy length and area measurements with a manual IVUS pullback.
Simplifies vessel sizing/measurement
IVUS Co-registration provides easy length measurement with manual IVUS pullback and area/diameter measurements for accurate stent sizing. This feature also provides automated, real-time side-by-side display of co-registered IVUS and angio images to help correlate critical and anatomical landmarks, especially in complex cases, such as bifurcations.⁴, ⁷, ¹⁰, ¹¹
Angio+ device positioning
The SyncVision Angio+ device positioning tool provides enhanced visualization of device position within the vessel and is designed to help reduce risk of geographic miss, which study data suggests may occur in 66.5% of PCIs.¹
Healthy-to-healthy landing zones
Intravascular ultrasound guidance helps to confirm healthy-to-healthy landing zones, according to clinical research.³
Angio+ device inflation
SyncVision Angio+ device inflation provides enhanced visualization of balloon to observe proper inflation. Successful cardiovascular treatment relies on proper balloon inflation, and enhanced imaging can help determine successful inflation functioning.⁸
Angio+ device enhancement
SyncVision Angio+ device enhancement provides enhanced visualization of stent deployment under fluoroscopy to help ensure proper deployment and correct location of deployment.
Streamlines and simplifies therapy
SyncVision streamlines lesion assessment with co-registration and vessel enhancement, simplifying vessel sizing with real-time QCA and easy length/area/diameter measurement. SyncVision enables precise therapy delivery with Angio+ device detection, offering live stabilization and image enhancement, real-time post-acquisition image processing, and IVUS to assist with confirmation.
IVUS helps with disease assessment
IVUS imaging helps physicians assess disease markers, including plaque burden percentage, lesion location and morphology, calcium volume, and the presence of thrombus. It also provides analysis of crucial parameters—like luminal cross-sectional measurements—and helps aid in disease diagnosis.
Fractional Flow Reserve measurement
Various clinical studies demonstrate that physiologic lesion assessment by FFR to guide routine PCI is superior to current angiography guided treatment. This measured ratio represents the potential decrease in coronary flow distal to the coronary stenosis.¹⁴
iFR modality simplifies workflow
iFR modality simplifies workflow by providing a hyperemia-free measurement to assess lesion significance in as few as five heartbeats. Philips’ proprietary iFR modality has a robust body of clinical evidence with over 9,000 patients in numerous studies and peer-reviewed journal articles.¹³
iFR Scout pullback
The iFR Scout pullback shows the most significant gradient in the mid-vessel lesion with diffuse proximal disease.
1. Costa, Angiolillo DJ, Tannenbaum M, et al. Impact of Stent Deployment Procedural Factors on Long-term Effectiveness and Safety of Sirolimus-Eluting Stents (Final results of the Multicenter Prospective STLLR Trial). Am J Cardiol. 2008; 101(12):1704-1711.
2. Renata Rogacka, Azeem Latib, Antonio Colombo. IVUS-Guided Stent Implantation to Improve Outcome: A Promise Waiting to be Fulfilled. Curr Cardiol Rev. 2009;5(2):78–86.
3. Witzenbichler B, Maehara A, Weisz G, et al. Relationship Between Intravascular Ultrasound Guidance and Clinical Outcomes After Drug-Eluting Stents: The ADAPT-DES Study. Circulation. 2014;129:463-470.
4. 202-0013.53 SRS, Sync-Rx System pg 19,24.
5. Jakabcin J1, Spacek R, Bystron M, et al. Long-term health outcome and mortality evaluation after invasive coronary treatment using drug eluting stents with or without the IVUS guidance. Randomized control trial. HOME DES IVUS. Catheter Cardiovasc Interv. 2010;75(4):578-583.
6. 209-0030.02 Test Rpt, Use Validation, SyncVision. Pg. 9, Section 10.3; pg 14 – results.
9. Patel, et al. ACCF/SCAI/STS/AATS/AHA/ASNC/HFSA/SCCT 2012 Appropriate use criteria for coronary revascularization focused update: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, American Association for Thoracic Surgery, American Heart Association, American Society of Nuclear Cardiology, and the Society of Cardiovascular Computed Tomography. J Am Coll Cardiol. 2012;59(9):857-881.
10. Kim SH, Kim YH, Kang SJ, et al. Long-term outcomes of intravascular ultrasound-guided stenting in coronary bifurcation lesions. Am J Cardiol. 2010;106(5):612-618.
11. Patel Y, Depta JP, Novak E, et al. Long-term outcomes with use of intravascular ultrasound for the treatment of coronary bifurcation lesions. Am J Cardiol. 2012;109(7):960-965.
12. Davies JE, et al. Coronary artery physiological stenosis mapping: application of pressure wire technology to measure stenosis significance, length, and predict the outcome of intervention. Abstract presented at PCR 2014
13. An iFR cut-point of 0.89 matches best with an FFR ischemic cut-point of 0.80 with a specificity of 87.8% and sensitivity of 73.0%. (iFR Operator’s Manual 505-0101.23)
14. Fractional Flow Reserve–Guided PCI versus Medical Therapy in Stable Coronary Disease. N Engl J Med. 2012;367(11):991-1001.
*Data on file
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